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Symbol
Name
ID

Grm1
glutamate receptor, metabotropic 1
MGI:1351338

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Dysphagia

Spasticity

Frequent falls

Dilated fourth ventricle

Inferior cerebellar vermis hypoplasia

Cerebellar atrophy

Retrocerebellar cyst

Ataxia

Dysdiadochokinesis

Dysmetria

Gait ataxia

Tremor

Abnormal pyramidal sign

Absent speech

Delayed speech and language development

Dysarthria

Intellectual disability

Hyperreflexia

Brisk reflexes

Inability to walk

Global developmental delay

Severe global developmental delay

Motor delay

Polyneuropathy

Seizure

Disease(s) Associated with GRM1

autosomal recessive spinocerebellar ataxia 13

spinocerebellar ataxia 44

Mouse Phenotypes		nervous system phenotype	abnormal nervous system electrophysiology	abnormal excitatory postsynaptic currents	short excitatory postsynaptic current decay time	reduced long-term potentiation	reduced long-term depression
Availability	Mouse Genotype	nervous system phenotype	abnormal nervous system electrophysiology	abnormal excitatory postsynaptic currents	short excitatory postsynaptic current decay time	reduced long-term potentiation	reduced long-term depression
	Grm1^crv4/Grm1^crv4	*
	Grm1^rcw-3J/Grm1^rcw-3J	*
	Grm1^rcw-4J/Grm1^rcw-4J
	Grm1^tm1Crpl/Grm1^tm1Crpl
	Grm1^tm1Kyo/Grm1^tm1Kyo
	Grm1^tm1Stl/Grm1^tm1Stl	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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